They didn't lie to you in elementary school, being different is awesome.
In high school and my early twenties I was teased for wearing video game related t-shirts. Now the the same girls who teased me often complain to me over facebook about being suck in generic relationships and "wish they had found something to love the way I love gaming". Also, I recently made a bet that my $15 TMNT purse would get more compliments at a bar than a $900 coach purse. I won.
Wheaton adds one piece of advice of his own, which you can peruse over at his blog. It involves "not being a dick", and is good advice to most people under 20, and lots over 20.
Having a few close friends is better than a huge group of associates.
I somehow became the cool nerd girl when I moved to my current city. I went to a different party every night of the week. It's so pathetic to admit this, but in a month I went from having around 33 pics of me on facebook to over 300. I felt cool. Then I had an issue I needed to talk to someone about. All of my cool friends were as helpful as paper weights in a hurricane. I went back to my small group of "unpopular" friends. They helped me through my issue and loved me just the same.